Intravenous (IV) Ketamine
IV ketamine is as an anesthetic medication that is also used for treatment resistant depression. Numerous clinical trials have demonstrated that IV ketamine has rapid and robust antidepressant effects in individuals who continue to suffer from depression, despite trying numerous antidepressant medications and psychotherapy. IV ketamine is used ‘off label’ for depression, meaning that it has not been Health Canada approved for this specific indication.
Oral Ketamine Tablets
Ketamine is compounded into an oral tablet that dissolves under your tongue. Oral ketamine is used off-label for treatment resistant depression. Initial clinical trials have shown promising results; however, oral ketamine is less studied compared to IV ketamine and nasal esketamine. Oral ketamine is associated with significant dissociative effects, similar to IV ketamine. As such, oral ketamine is administered in the clinic where you are monitored by trained healthcare professionals to ensure a safe and supported treatment experience.